The current state of uterine cervical cancer reflects both advancements and ongoing challenges. Despite progress in prevention through HPV vaccination and early detection via regular screenings, the disease remains a significant public health concern, especially in low-resource settings. In many regions, limited access to healthcare services, lack of awareness, and delayed diagnosis contribute to higher morbidity and mortality rates. Continued efforts in education, accessible healthcare, and inn
Conditions
Interventions
A population of 270 participants will be included in the study to monitor the HPV clearance rate at intervals of 3, 6, 12, 18, and 24 months using the Allplex HPV HR detection test. The participants w
Diagnostic
Cervical cancer group
Sponsors
Faculty of Medicine Siriraj Hospital Mahidol University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Female patients diagnosed with cervical cancer receiving treatment at Siriraj Hospital. 2. Age since 18 years. 3. Not pregnant. 4. Able to communicate in Thai. 5. Must have signed a consent form to participate in the research after reading the documents and asking questions about the study until fully understood. 6.Pathological results of all types.
Exclusion criteria
Exclusion criteria: 1. Female patients who have not returned for follow-up examinations after treatment. 2. High-risk HPV has not been detected since the initial diagnosis (non-HPV-related cervical cancer). 3. When a woman declines to participate in the research at any time. 4.Use of zinc sulfate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HPV clearance 0, 3, 6, 12, 18, and 24 months Measurement of HPV DNA less 1-5 copies per cell, mRNA shoud don't have in specimen, and cell-free HPV DNA obtained don't express from blood and swab samples of participant | — |
Secondary
| Measure | Time frame |
|---|---|
| Survival of participant 24 year Monitoring the survival time of participants (Survival follow-up) | — |
Countries
Thailand
Contacts
Public ContactAssoc. Prof. Irene Ruengkhachorn
Gynecologic oncology division of obstetrics and gynecology
Outcome results
None listed