The Effects of Remote Ischemic Preconditioning in Patients with Ischemic-reperfusion Injury from Acute Non-traumatic Limb Ischemia

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20241022007

Enrollment

Registered

2024-10-22

Start date

2021-03-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischemia repercussion injury limb ischemia Mitochondrial dysfunction ischemic preconditioning

Interventions

inflated until reach 200 mmHg ,sham Comparator group, blood pressure cuff was inflated equal to venous blood pressure

Experimental Procedure/Surgery,Sham Comparator Procedure/Surgery

Remote ischemic preconditioning,Sham Comparator

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Patient who diagnosed Acute limb ischemia and perform surgical revascularization in Maharaj-nakorn-chiangmai

Exclusion criteria

Exclusion criteria: 1.acute limb ischemia Rutherford class 3 2.glomerular filtration rate <30 mL/min/ 1.73 square meter 3.Previous upper extremities surgery 4.Upper extremities peripheral artery disease

Design outcomes

Primary

Measure	Time frame
Creatinine clearance 24 hr Creatinine Clearance (Cockcroft-Gault Equation),plasma Neutrophil Gelatinase-associated Lipocalin 24 hr ELISA kit (Sigma, USA)	—

Secondary

Measure	Time frame
local organ effect at post revascularization time clinical of compartment syndrome by measure intracompartmene pressure of leg after revascularization	—

Countries

Thailand

Contacts

Public ContactPoon Apichartpiyakul

Faculty of Medicine, Chiang Mai University

lordpoons@gmail.com0869149254

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026