Mild to moderate acne Acne
Conditions
Interventions
apply CBD cream,apply Clindamycin cream
CBD group,Clindamycin cream
Sponsors
Thammasat University Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Patients with mild to moderate acne severity, based on the acne severity criteria of the U.S. Food and Drug Administration (US FDA), who are receiving treatment at the Dermatology Center of Thammasat University Hospital and are between 18 and 35 years old. Participants agree to discontinue the use of other facial skincare products throughout the study period, including other procedures such as acne extraction, facial treatments, and laser treatments. Participants are able to comply with the testing procedures, attend follow-up appointments throughout the study period, and can immediately report any side effects that occur from the research.
Exclusion criteria
Exclusion criteria: Volunteers who are unwilling to participate in the research or cannot read, write, listen to, or understand the Thai language. Volunteers who have been treated for acne with medications not provided under the research project or who are taking antibiotics during the research period. Volunteers with other skin diseases that cause facial rashes, such as Systemic Lupus Erythematosus (SLE) or psoriasis. Volunteers who are taking certain dietary supplements that affect acne. Volunteers who are pregnant, suspect they are pregnant, or are breastfeeding. Volunteers with certain underlying conditions such as Cushing's syndrome or immunodeficiency diseases. Volunteers who have taken contraceptive pills in the past 6 months. Volunteers with a history of taking isotretinoin in the past 6 months. Volunteers with a history of using topical acne treatments such as 2.5% Benzoyl Peroxide, retinoids, or nicotinamide within at least the past 4 weeks before joining the study. Volunteers with a history of using antibiotics in the past 4 weeks, such as Doxycycline, Clindamycin, or Augmentin (Amoxicillin and Clavulanate). Volunteers with a history of taking vitamins that can affect acne, such as vitamin C, vitamin E, or vitamin A, in the past 4 weeks. Volunteers who have a known allergy to Clindamycin and/or 2.5% Benzoyl Peroxide.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of acne lesion 12 week Number of acne lesion | — |
Secondary
| Measure | Time frame |
|---|---|
| Acne severity 12 Acne severity according to Investigator's Global assessment score,Photo evaluation 12 week Photo evaluation,Patient satisfaction score 12 week 9-Point-Patient satisfaction score,Quality of life score 12 week Thai version of the Dermatology Life Quality Index (DLQI),Adverse event 12 week Number of adverse event,Compliance 12 week Number of use per week | — |
Countries
Thailand
Contacts
Public ContactPanlop Chakkavittumrong
Thammasat University Hospital
Outcome results
None listed