HCC patients receiving TACE treatment. Spleen stiffness, Hepatocellular carcinoma, HCC, liver decompensation, hepatic decompensation
Conditions
Interventions
Patients with Measurement of spleen stiffness day 10 after TACE in HCC patients.,Patients with Measurement of spleen stiffness day 28 after TACE in HCC patients.
Diagnostic,Diagnostic
Day 10 after TACE,Day 28 after TACE
Sponsors
Faculty of Medicine, Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adult > 18-year-old 2. HCC patients receiving TACE, regardless of the number of TACE sessions.
Exclusion criteria
Exclusion criteria: 1. post-LT patients 2. Patients with spontaneous hepatocaval shunt 3. Post-transients Transjugular intrahepatic portosystemic shunt (TIPS) 4. Post-splenectomy, patients with history of splenic infarction, patients with history of splenic vein thrombosis 5. Patients with myelofibrosis 6. Patients with contraindication for TACE eg. AKI, extensive HCC unsuitable for TACE, liver failure, acute GI bleeding, active variceal bleeding, hepatic encephalopathy, uncorrectable coagulopathy, comorbidity to high risk for TACE 7. Patients with inconvenience will be included in the trial. 8. Patients with repeated TACE within 4 weeks after included in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of spleen stiffness 10 days 2D-shear wave elastrography,change of spleen stiffness 4 weeks 2D-shear wave elastrography | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of hepatic decompensation after TACE 6 months clinical ascites, hepatic encephalopathy, SBP,liver stiffness after TACE 4 weeks 2D-shear wave elastrography | — |
Countries
Thailand
Contacts
Public ContactChidkamon Pattarawongpaiboon
King Chulalongkorn Memorial Hospital
Outcome results
None listed