severe cardio-pulmonary failure required ECMO therapy ARDS, cardiogenic shock, refractory, ECMO, outcome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 Infants, Children and Adults aged between Newborn through 18 year old (Ped) and Adult age more than 18 years to 80 years with diagnosis of Acute severe cardio-pulmonary or cardiovascular failure and required extracorporeal life support 2 No Exclusion Criteria eg Multiple organ failure
Exclusion criteria
Exclusion criteria: End- stage disease e.g. advanced metastasis tumors - Severe congenital anomaly - Age > 80 years old - Terminal Illness or Limited Life Expectancy: Exclude participants with terminal illnesses or a limited life expectancy, as ECMO is typically considered a treatment option for reversible conditions. - Uncontrolled Bleeding or Coagulation Disorders: Exclude individuals with severe bleeding disorders or coagulopathy that cannot be adequately managed during ECMO support. - Severe Neurological Injury: Exclude participants with severe neurological injury or irreversible brain damage, as ECMO may not be beneficial in these cases. - Inability to Provide Informed Consent: Exclude participants who are unable to provide informed consent themselves or lack a legally authorized representative to provide consent on their behalf.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| survival at hospital discharged Rate of survival,Morbidity any time point during ecmo treatment bleeding,ICU Ventilator day 28 days of ICU admission days on Ventilator in ICU | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life End of hospital discharged Clinical Score | — |
Countries
Thailand
Contacts
King Chulalongkorn Memorial Hospital