Biophysical profile score and Doppler flow parameters. Biophysical activities, dexamethasone, Doppler flow.
Conditions
Interventions
Participants receiving 6 mg of dexamethasone by intramuscular injection every 12 hours for 4 doses.,Participants receiving 5 mg of dexamethasone by intramuscular injection every 12 hours for 4 doses.,
Dexa 6 mg,Dexa 5 mg,Dexa 4 mg
Sponsors
Navamindradhiraj University
Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 years or more. 2. Singleton pregnancy. 3. Gestational age between 29+0 - 36+6 weeks. 4. Having a clinical diagnosis of preterm labor. 5. Willingness to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Having a history of dexamethasone receiving before 29 weeks of gestation. 2. Having a history of steroid allergy. 3. Having any signs or symptoms of infection at the time of enrollment. 4. Receiving insulin or any oral hypoglecemic agent treatment. 5. Being unavailability to undergoing ultrasound examination before the commencement of dexamethasone. 6. Delivery before receiving the four doses of dexamethasone.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biophysical profile pre-treatment, and at 24 hours , 48 hours, 72 hours, and 96 hours after commencement of first dose of dexamethasone Biophysical profile score | — |
Secondary
| Measure | Time frame |
|---|---|
| Dopple velocity pre-treatment, and at 24 hours , 48 hours, 72 hours, and 96 hours after commencement of first dose of dexamethasone Umbilical artery Doppler pulsatility index and middle cerebral artery Doppler pulsatility index | — |
Countries
Thailand
Contacts
Public ContactChadakarn Phaloprakarn
Faculty of Medicine Vajira Hospital
Outcome results
None listed