postoperative dizziness in patients receiving spinal anesthesia with intrathecal morphine undergoing open gynecologic surgery ERAS, Dimenhydrinate, dizziness, vertigo, postoperative dizziness, postoperative motion sickness, side effect of spinal anesthesia, side effects of intrathecal morphine, side effects of dimenhydrinate
Conditions
Interventions
Dimenhydrinate 50 mg intramuscular,Normal saline 2 ml intramuscular
Experimental Drug,Placebo Comparator Drug
Dimenhydrinate,Control
Sponsors
King Chulalongkorn University Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients schedule for elective open gynecologic surgery 2. Received spinal anesthesia with 0.5% hyperbaric bupivacaine and morphine 0.2 mg 3. ASA PS I- II
Exclusion criteria
Exclusion criteria: 1.Allergy/Have side effects after received dimenhydrinate, allergy to benzyl alcohol, allergy to propylene glycol 2.Using drug in barbiturate group 3.Have history of receiving ototoxic drugs eg. aminoglycoside, cisplatin, loop diuretics, salicylates, vancomycin 4.Have cardiovascular underlying condition eg. dysarrhythmia 5.Contraindicated/refuse to spinal anesthesia 6.Anesthetic level (sensory block) after spinal block below T6 7.Patient refusal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative dizziness at 24 hours postoperative Dizziness score | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative dizziness at 24 hours postoperative University of Michigan Sedation Scale (UMSS) | — |
Countries
Thailand
Contacts
Public ContactWitchayaporn Boonsup
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed