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Oxygen reserve index guided (ORI) individualized optimal positive end expiratory pressure (PEEP) in patients undergoing gynecologic laparoscopic surgery

Oxygen reserve index guided (ORI) individualized optimal positive end expiratory pressure (PEEP) in patients undergoing gynecologic laparoscopic surgery

Status
Unknown
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20241009004
Enrollment
45
Registered
2024-10-09
Start date
2024-04-19
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic surgery PEEP titration Oxygen reserve index lung compliance positive end expiratory pressure lung compliance

Interventions

1. Recruitment maneuver After the patient is placed in trendelenburg position and CO2 insufflation, measure the angle of inclination of the surgical bed relative to the floor level and all paramet
Experimental Procedure/Surgery
Recruitment maneuver and PEEP titration

Sponsors

Faculty of medicine, Chiangmai University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) physical status 1-2 2. Age of 20 to 65 years old 3. Body mass index (BMI) less than 30 kg/m2 4. Candidates for elective laparoscopic surgery under general anesthesia with an expected duration of > 2 hr

Exclusion criteria

Exclusion criteria: 1. Patients who refuse to provide informed consent or are participating in another interventional study 2. Severe cardiac disease defined as New York Heart Association grade III or IV 3. Previous lung surgery or history of pulmonary disease 4. Allergy to anesthetic agents 5. Emergency surgery 6. Pregnancy

Design outcomes

Primary

MeasureTime frame
Correlation of ORI and static compliance (Cstat) at each PEEP level Oxygen reserve index and static compliance

Secondary

MeasureTime frame
Optimal PEEP of gynecologic laparoscopic surgery and ORI value at optimal PEEP guided by Cstat at level of best lung static compliance PEEP and oxygen reserve index

Countries

Thailand

Contacts

Public ContactSuraphong Lorsomradee

Faculty of medicine, Chiangmai University

slorsomr@yahoo.com086 197 2167

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026