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Pilot study of The Effect of Ayurved Siriraj Wattana formula (WNF) on Evaluation of Clinical measurements and Metabolomics profiles in Heathy Older Volunteers

Pilot study of The Effect of Ayurved Siriraj Wattana formula (WNF) on Evaluation of Clinical measurements and Metabolomics profiles in Heathy Older Volunteers

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20241008005
Enrollment
40
Registered
2024-10-08
Start date
2020-03-05
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers aged 60 years or older with either no medical conditions or mild/stage 1 conditions that do not require medication and are approved by a doctor. aging, healthy aging, older, herbal medicine, Ayurved Siriraj Wattana formula

Interventions

Take 3 pills (200 mg / pill) of WNF 3 times per day before meals. Administered for 8 weeks (2 month)
Experimental Drug

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Healthy Thai volunteers aged 60 years or older. 2. No medical conditions or having mild/stage1 medical conditions that not using medication to treat and approved by a doctor. 3. Having Body Mass Index (BMI) between 18.5-29.99 Kg/m2. 4. Voluntarily participate in the study.

Exclusion criteria

Exclusion criteria: 1. Have history of herbal medicine allergy. 2. Smoke, drink alcohol and/or other beverages with alcoholic ingredients regularly. 3. Have received other medications, or other herbal medicine within 14 days prior to the study period. 4. The clinical chemistry laboratory results of liver and kidney functions are out of the reference ranges 5. The results of complete blood count (CBC) are out of the reference ranges

Design outcomes

Primary

MeasureTime frame
Arterial Stiffness 0,14,28 days and 8 weeks. baPWV,Metabolomics profiles 0,14,28 days and 8 weeks. LC-MS study,present Dhatu Chao Ruean (pDCR) 0,14,28 days and 8 weeks. pDCR analysis questionnaire

Secondary

MeasureTime frame
Safety 0,14,28 days and 8 weeks. Blood urea nitrogen (BUN) Creatinine (CREA) Aspartate transaminase (AST) Alanine aminotransferase (ALT) Alkaline Phosphatase (ALP) Total bilirubin

Countries

Thailand

Contacts

Public ContactPravit Akarasereenont

Faculty of Medicine Siriraj Hospital, Mahidol University

pravit.auk@mahidol.edu024191705

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026