Healthy volunteers aged 60 years or older with either no medical conditions or mild/stage 1 conditions that do not require medication and are approved by a doctor. aging, healthy aging, older, herbal medicine, Ayurved Siriraj Wattana formula
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy Thai volunteers aged 60 years or older. 2. No medical conditions or having mild/stage1 medical conditions that not using medication to treat and approved by a doctor. 3. Having Body Mass Index (BMI) between 18.5-29.99 Kg/m2. 4. Voluntarily participate in the study.
Exclusion criteria
Exclusion criteria: 1. Have history of herbal medicine allergy. 2. Smoke, drink alcohol and/or other beverages with alcoholic ingredients regularly. 3. Have received other medications, or other herbal medicine within 14 days prior to the study period. 4. The clinical chemistry laboratory results of liver and kidney functions are out of the reference ranges 5. The results of complete blood count (CBC) are out of the reference ranges
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Arterial Stiffness 0,14,28 days and 8 weeks. baPWV,Metabolomics profiles 0,14,28 days and 8 weeks. LC-MS study,present Dhatu Chao Ruean (pDCR) 0,14,28 days and 8 weeks. pDCR analysis questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety 0,14,28 days and 8 weeks. Blood urea nitrogen (BUN) Creatinine (CREA) Aspartate transaminase (AST) Alanine aminotransferase (ALT) Alkaline Phosphatase (ALP) Total bilirubin | — |
Countries
Thailand
Contacts
Faculty of Medicine Siriraj Hospital, Mahidol University