Intranasal capsaicin has been reported to be beneficial in non allergic rhinitis symptom control. capsaicin nasal spray, non allergic rhinitis
Conditions
Interventions
0.01mM capsaicin nasal spray was used to apply 2puff once daily each nostril every day for 2 weeks.,0.05mM capsaicin nasal spray was used to apply 2puff once daily each nostril every day for 2 weeks.
Active Comparator Drug,Active Comparator Drug
0.01mM capsaicin nasal spray,0.05mM capsaicin nasal spray
Sponsors
Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patient who was diagnosed non allergic rhinitis
Exclusion criteria
Exclusion criteria: 1.Use of systemic or inhaled corticosteroids in the previous month. 2.History of nasal surgery 3.Cormobid of nasal polyps or sinonasal tumor. 4.Comorbid of significant anatomical abnormalities affecting nasal function. 5.Comorbid of nasal or paranasal sinus infection 6. Patient who has drug-induced rhinitis, inability of the patient to stop taking medication affecting nasal function. 7.History of capsaicin allergy. 8.Pregnancy or lactation. 9.Smoking 10.Comorbid of asthma or atopic dermatitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of capsaicin nasal spray in non allergic rhinitis patients. within two weeks after end of the intervention compare visual analogue scale of nasal symptoms before and after intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects of capsaicin nasal spray within two weeks after end of the intervention percentage of side effects | — |
Countries
Thailand
Contacts
Public ContactTriphoom Suwanwech
Siriraj Hospital
Outcome results
None listed