radiation caries(rapid and extensive tooth decay) in Head and neck cancer patients who have undergone radiation therapy Radiation caries, Silver diamine fluoride, Sodium fluoride varnish, Head and neck cancer, Radiation therapy
Conditions
Interventions
using cotton pellet to apply 38% Silver diamine fluoride around Buccal, Lingual, and proximal surface of the teeth for 1 minute (1 drop/5 teeth) every 6 months,using micro brush to apply 5% Sodium flu
Experimental Drug,Active Comparator Drug
Silver diamine fluoride application,Sodium fluoride varnish application
Sponsors
-
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patient with head and neck radiation therapy who have completed radiotherapy more than 1 month and less than 3 months 2.Age greater than or equal to 18 years old 3.Complete dental treatment 4.Have at least 5 teeth
Exclusion criteria
Exclusion criteria: 1.Incapable of accessing dental treatment due to limited mouth opening 2.Allergic to silver or colophony agents 3.Presence of oral mucositis at randomization day 4.Received head and neck radiation more than 1 course 5.Regular use Fluoride mouth rinse or Fluoride tray
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of tooth surfaces develop to new caries or restorations from first recall dental visit until 2 years decayed, missing, filled teeth indices (DMFS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Contributing factors that affect radiation caries from first recall dental visit until 2 years assess data from demographic data and medical record | — |
Countries
Thailand
Contacts
Public ContactPipop Saikaew
Mahidol University
Outcome results
None listed