Patients with healthy conditions who presented with posterior partial edentulous area more than 2 months after tooth extraction require to receive guided bone regeneration simultaneous with implant placement alveolar ridge augmentation Platelet-Rich Fibrin
Conditions
Interventions
the about 2 ml of normal saline soaking with xenograft in the adequate amount in order to hydrating the xenograft before loading into grafting site with appropriate amount. The grafted site will be co
Placebo Comparator Procedure/Surgery,Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
GBR mixed with normal saline,GBR mixed with autologous blood,GBR mixed with i-PRF
Sponsors
Facalty of Dentistry, Chulalongkorn University, Bangkok, Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Healthy Thai patients age >18 years (American Society Anesthesiologists (ASA) class I & II) 2. Patients who have single tooth or 2-adjacent teeth edentulous area with history of tooth extraction more than 2 months and require horizontal bone augmentation simultaneous with dental implant placement in posterior regions of mandible.
Exclusion criteria
Exclusion criteria: 1. Patients with uncontrolled systemic conditions, such as uncontrol hypertension, diabetes and bone metabolism disorders, or local conditions that interfere the wound healing process. 2. Patients exhibiting parafunctional habits such as bruxism or clenching. 3. Patients with poor oral hygiene or lacking motivation for oral care. 4. Patients currently undergoing treatment that may interfere with osseointegration, such as antiresorptive drugs or long-term steroid therapy. 5. Patients with a history of head and neck radiotherapy or undergoing chemotherapy. 6. Patients with a history of alcohol or drug abuse. 7. Patients who smoke. 8. Patients who are pregnant or lactating. 9. Patients unable to attend follow-up appointments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone Thickness 2 time points, immediate post-operation and 6 month follow-up Using Cone-beam computed tomography, with 2 time points. | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-op Pain and Swelling 7 days after surgery Patient Reported Outcome,Clinical Outcomes 14 days after surgery and stitches off appointment Doctor's note and patient's follow-up record | — |
Countries
Thailand
Contacts
Public ContactNitipat Khangrang
Faculty of Dentistry, Chulalongkorn University
Outcome results
None listed