Skip to content

Outcomes of 16 Weeks of Combined Exercises on Cobb Angle, Bone and Muscle Health, and Quality of Life in Females with Idiopathic Scoliosis: A Study Protocol for a Single-Blinded Randomized Controlled Trial

Exercise intervention for females with idiopathic scoliosis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20241001001
Enrollment
28
Registered
2024-10-01
Start date
2024-12-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic scoliosis Scoliosis Spinal malalignment

Interventions

The combined exercise program, incorporating Schroth, core stabilization, and impact-loading components, will be performed for 50-70 minutes per session, three times per week over a 16-week period.,Th
Experimental Other,Active Comparator Other
Schroth exercises, core stabilization, and impact-loading exercises ,Schroth exercises and core stabilization

Sponsors

None listed

Eligibility

Sex/Gender
Female
Age
15 Years to 19 Years

Inclusion criteria

Inclusion criteria: Females aged 15-19 years who have been recently diagnosed with IS by a physician without medical contraindications to physical activity and prior prescription for conservative interventions for IS (e.g., bracing, physical therapy, scoliosis-specific exercise, or surgery). Participants must also have upright standing plain radiographs, either full-length spine or segmental thoracic and lumbar views, taken within the past three months and showing a Cobb angle between 10 and 40 degrees.

Exclusion criteria

Exclusion criteria: Participants will be excluded if they have any cardiovascular, endocrine, or connective tissue disorders affecting musculoskeletal health; gastrointestinal or eating disorders affecting nutrient absorption; current use of medications that influence bone or muscle metabolism; high physical activity levels (IPAQ score more than 3,000 MET-min/week); and high-risk behaviors such as smoking or alcohol consumption.

Design outcomes

Primary

MeasureTime frame
whole body bone mineral density (BMD) At baseline and at the end of the 16-week intervention DEXA,Non-dominant leg mineral density (BMD) At baseline and at the end of the 16-week intervention DEXA

Secondary

MeasureTime frame
Spinal flexibility At baseline, and at 4-, 8-, and 12-week follow-ups, and at the end of the 16-week intervention Modified Schober test ,Core muscle endurance At baseline, and at 4-, 8-, and 12-week follow-ups, and at the end of the 16-week intervention Prone plank,Cosmetic deformity At baseline, and at 4-, 8-, and 12-week follow-ups, and at the end of the 16-week intervention Walter Reed Visual Assessment Scale ,Quality of life At baseline, and at 4-, 8-, and 12-week follow-ups, and at the end of the 16-week intervention Scoliosis Research Society-22 questionnaire,Lean body mass At baseline and at the end of the 16-week intervention DEXA,Cobb angle At baseline and at the end of the 16-week intervention DEXA,Exercise adherence Weeks 1-16, cumulative at week 16 Percentage of completed sessions (out of 48), based on online logbook, photo submissions, and monthly clinic visits,Exercise compliance Weeks 1-16, cumulative at week 16 Percentage of sessions completed per protocol, based on online logbook,Exertion monitoring At the end of each exercise session Modified Borg CR10 Scale

Countries

Thailand

Contacts

Public ContactNuanlaor Thawinchai

Faculty of Associated Medical Sciences, Chiang Mai University

nuanlaor.thawinchai@cmu.ac.th6653949242

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026