Idiopathic Sudden Sensorineural Hearing Loss patient , within 4 weeks from onset who have not received treatment with steroids berfore or patient who have previously been treated with systemic steroids and have not response to treatment intratympanic injection,Idiopathic Sudden Sensorineural Hearing Loss , dexamethasone,Methylprednisolone
Conditions
Interventions
dexamethasone 5mg/ml of Intratympanic injection ,methylprednisolone injection of Intratympanic injection
Experimental Drug,Active Comparator Drug
intratympanic injection : dexamethasone,intratympanic injection : methylprednisolone
Sponsors
Faculty of medicine Chulalongkorn university
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 80 years diagnosed with SSNHL, characterized by a loss of sensorineural hearing of at least 30 dB at three consecutive frequencies, as confirmed by Audiogram, and all symptoms occurring within 72 hours. 2. Patients with hearing loss in only one ear. 3. Patients with SSNHL within 4 weeks from onset who have not received treatment with steroids before this or patients who have previously been treated with systemic steroids and have not responded to the treatment.
Exclusion criteria
Exclusion criteria: 1. Patients with hearing loss due to known causes such as accidents, self-immune deficiency, middle ear inflammation, unequal ear fluid, retro cochlear lesion, exposure to nerve-affecting drugs, and hearing loss from radiation. 2. Patients with fluctuating hearing loss or a history of previous hearing loss
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pure tone average/speech discrimination score of post treatment at 4 week after end of the intervention audiogram (decibel),% | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score in first intratympanic injection at 4 week after end of the intervention visual analog scale | — |
Countries
Thailand
Contacts
Public ContactNoppadon madawa
Department of otolaryngology
Outcome results
None listed