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Effect of Chlorhexidine and Tea-Tree-Oil Mouthwashes on Clinical-Parameters, Lactobacilli, Candida-Albicans, Salivary-pH and AST Enzyme in Plaque-induced Gingivitis Patients

Effect of Chlorhexidine and Tea-Tree-Oil Mouthwashes on Clinical-Parameters, Lactobacilli, Candida-Albicans, Salivary-pH and AST Enzyme in Plaque-induced Gingivitis Patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240926003
Enrollment
43
Registered
2024-09-26
Start date
2024-05-14
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

clinical measurement of plaque index(PI) gingival index(GI) lactobacilli , candida albicans , AST enzyme and salivary pH will be evaluated at baseline , 7 days , 14 days and 28 days CHX ,TTO , Lactobacilli, AST enzyme , salivary pH

Interventions

The patients were given 3 bottles containing 100 ml of CHX mouthwash for each bottle, They were instructed to rinse for 1 minutes with 10 ml of the mouthwash two times daily,30 minutes after tooth b
Experimental Drug,Experimental Drug
chlorhexidine mouthwash CHX,tea tree oil mouthwash TTO

Sponsors

hospital of stomatology of Sana'a university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Good overall condition( patients without systemic diseases), availability for the four weeks interval of the study. Patients who have evidence of plaque-induced gingivitis without periodontitis, and at least 20 natural teeth, excluding third molars. Systemically free of any disease. Non-smokers

Exclusion criteria

Exclusion criteria: Periodontitis patients Patients who have orthodontic bands or partial removable dentures. Pregnant or breastfeeding women Subjects with a history of allergic to oral user drugs Subjects who received antibiotic therapy or taking any medication in the last 3 months before entering into the study

Design outcomes

Primary

MeasureTime frame
plaque score and gingival score 7 days , 14 days, 28 days plaqe and gingival indices

Secondary

MeasureTime frame
lactobacilli, candida albicnas , AST enzyme , salivary pH 7 days , 14 days , 28 days plaque sample for cultivation , salivary samples

Countries

Yemen

Contacts

Public ContactHadeel Abualgaith

stomatology hospital of sanaa university

leedahamn92@gmail.com00967779809190

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026