Constipation Menopausal symptoms Menopausal women Functional constipation Probiotics
Conditions
Interventions
Probiotic formulation consisting of 8-strain probiotic with 10 billion CFU per capsule,Maltodextrin, Magnesium stearate, Silicone dioxide, Hydroxypropyl methyl cellulose, Titanium dioxide, Carrageenan
Experimental Dietary Supplement,Placebo Comparator Dietary Supplement
Probiotics ,Placebo
Sponsors
Phramongkutklao Hospital Foundation
Eligibility
Sex/Gender
Female
Age
45 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1.Women who absence of menstrual for greater or equal 12 months 2.Women who have been diagnosed with constipation according to the Rome IV criteria. 3.Informed consent 4.Good communicate with Thai language
Exclusion criteria
Exclusion criteria: 1. Individuals who have diseases or conditions that can cause constipation include: 1.1. Irritable bowel syndrome 1.2. Gastrointestinal cancer 1.3. Having thyroid disease and currently undergoing treatment 1.4. Post-radiation stricture of the intestines 2. Individuals who consume calcium supplements exceeding 1,500 milligrams per day 3. Individuals who have taken antibiotics, probiotics, prebiotics, or laxatives within the 2 weeks prior to participating in the research study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constipation Participants completed a questionnaire before starting the study and again after taking the medication for 4 weeks. Bristol Stool Form Scale and Additional symptom and dietary assessment tools | — |
Secondary
| Measure | Time frame |
|---|---|
| Menopausal symptoms The study involved completing a questionnaire both at the beginning and at the end of the 4-week medication period Menopause-specific Quality of Life Questionnaire (MENQOL) | — |
Countries
Thailand
Contacts
Public ContactNatita Nakapun
Phramongkutklao Hospital and College of Medicine
Outcome results
None listed