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Cycled versus Continuous Phototherapy for Treatment of Hyperbilirubinemia in Preterm Infants: A Feasibility Trial

Cycled versus Continuous Phototherapy for Treatment of Hyperbilirubinemia in Preterm Infants

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240921001
Enrollment
144
Registered
2024-09-21
Start date
2024-06-23
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

phototherapy in preterm infants continuous phototherapy cycled phototherapy

Interventions

On phototherapy 30 minutes then off phototherapy for 60 minutes then on phototherapy for 30 minutes then off phototherapy for 60 minutes and go on and follow total serum bilirubin every 12 hours,On p
Experimental Device,Active Comparator Device
Cycled phototherapy,Continuous phototherapy

Sponsors

Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
26 Weeks to 32 Weeks

Inclusion criteria

Inclusion criteria: Preterm infants GA 26 to 32 weeks with jaundice within 14 days after birth

Exclusion criteria

Exclusion criteria: 1. Infants outborn more than 24 h of age 2. History of previous phototherapy treatment 3. Major congenital anomaly 4. Severe illness (CVS instability required inotrope) 5. Infants who bilirubin reach exchange transfusion threshold before phototherapy

Design outcomes

Primary

MeasureTime frame
mean peak total serum bilirubin start until off phototherapy total serum bilirubin level,phototherapy exposure time start until off phototherapy case record

Secondary

MeasureTime frame
Rate of decline of serum bilirubin start until off phototherapy serum bilirubin,Infants who require escalation of care or blood transfusion start until off phototherapy case record,Infants who require retreatment of phototherapy phototherapy second time case record,Time to phototherapy discontinuation start until off phototherapy case record

Countries

Thailand

Contacts

Public ContactKantaporn Praikanarat

Mahidol University

bless_jane1994@hotmail.com66831807271

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026