post operative pain after undergo total knee arthroplasty in osteoarthritis knee requiring intravenous morphine injection total knee arthroplasty in osteoarthritis knee, post operative pain, morphine consumption, time to first rescue analgesia
Conditions
Interventions
Cocktail for intraoperative periarticular infiltration containing consist of magnesium
0.5% Bupivacaine 20 ml
epinephrine 0.5 ml
Dexamethasone 8 mg (2 ml)
additional 50% MgSO4 250 mg : by for
Experimental Drug,Experimental Drug
Magnesium base cocktail,conventional cocktail
Sponsors
Lerdsin Hospital, Thailand
Eligibility
Sex/Gender
All
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age more than 55 years old 2.Primary osteoarthritis 3.severity, Kellgren-lawrence grade 3 or 4 4.deformity degree 4.1 Varus/Valgus deformity less than 20 degree 4.2 Flexion contracture less than 20 degree 4.3 Recurvatum less than 15 degree 5. ASA classification 1 or 2
Exclusion criteria
Exclusion criteria: 1. ipsilateral hip pathology 2. neuromuscular disease 3. history of knee surgery or knee infection on planning site 4.communication problems 5. drug allergy as in protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first rescue analgesia Post operative period Time (duration after periarticular injection until fisrt rescue analgesia was requested) | — |
Secondary
| Measure | Time frame |
|---|---|
| pain score 3, 6, 12, 24, 36 hours post operative visual analogue score,total morphine consumption length of stay post operative milligram of morphine was prescribed I total length of stay,total morphine consumption in first 24 hours 24 hours post operative period milligram of morphine was prescribed in first 24 hours post operative period,functional score of total knee arthroplasty operation 6 months after operation Oxford knee score | — |
Countries
Thailand
Contacts
Public ContactSutivas Vaisiriroj
Lerdsin hospital
Outcome results
None listed