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Analgesic efficacy comparison between thoracolumbar interfascial plane block and wound infiltration technique following open lumbar spine surgery: A prospective double-blinded randomized controlled trial.

Analgesic efficacy comparison between thoracolumbar interfascial plane block and wound infiltration technique following open lumbar spine surgery: A prospective double-blinded randomized controlled trial.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240914003
Enrollment
48
Registered
2024-09-14
Start date
2024-10-07
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Degenerative lumbar spine surgery who required open spine surgery. thoracolumbar interfascial plane block, wound infiltration, postoperative pain control, spine surgery, multimodal analgesia

Interventions

In this group, patients will receive ultrasound-guided bilateral thoracolumbar interfacial plane block (TLIP block) with 0.25% bupivacaine with adrenaline ((1:200000 ) total 40 ml (20 ml per each side
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
TLIP block,WI

Sponsors

Faculty of Medicine, Khon Kaen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients who plan to undergo up to three levels of open lumbar spine surgery 2. Age over 18 years 3. ASA physical status 1-3

Exclusion criteria

Exclusion criteria: 1. Refuse to participate 2. Previous lumbar spine surgery 3. Spinal infection, spinal trauma and spinal metastasis 4. Allergy to study drugs; paracetamol, fentanyl, morphine, ketorolac, or bupivacaine 5. PNB contraindications include skin infection at the block site and coagulopathy 6. Body weight < 40 kg 7. Inability to cooperate, communicate, or report pain scores.

Design outcomes

Primary

MeasureTime frame
postoperative morphine consumption at PACU, 6h, 12h,24h and 48h total morphine consumption (mg) from IV PCA device—

Secondary

MeasureTime frame
postoperative pain score at PACU, 6h, 12h, 24h, and 48h Numeric rating pain score (patient self-report their pain intensity using 11-point scale from 0-10)—

Countries

Thailand

Contacts

Public ContactKriangkrai Wittayapairoj

Faculty of Medicine, Khon Kaen University

wkriang@kku.ac.th66805678957

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026