Amount of menstrual bleed in patient who use Estradiol valerate/dienogest and Ethinyl estradiol/desogestrel use Heavy menstrual blood loss, contraception, oral contraceptive pill, hormonal contraceptive pill
Conditions
Interventions
Oral contraceptive pills
Each wallet contains 26 colored active tablets and 2 white inactive-tablets.
ESTRADIOL VALERATE (3 mg, 2mg, 1mg)
DIENOGEST (2 mg, 3mg)
Take one tablet every day and should
Active Comparator Drug,Active Comparator Drug
Estradiol valerate/dienogest contraceptive pills ,Ethynyl estradiol/desogestrel contraceptive pills
Sponsors
Srinakharinwirot university
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1 Thai Female aged 18 to 40 years at the outpatient department of the HRH Princess Maha Chakri Sirindhorn Medical Center and who wish to use oral contraceptives for contraception. 2 Not currently taking hormonal medications for at least 6 months prior, or anticoagulant medications. 3 No history of drug allergies or adverse effects from hormonal medications.
Exclusion criteria
Exclusion criteria: 1 Body Mass Index greater than 30 kg per m2 2 Smoking more than 20 cigarettes per day 3 Patients with abnormal cervical cell test results, detected endometrial pathology, or abnormal uterine fibroids from transvaginal or abdominal ultrasound . 4 Patients with abnormal liver function test results from blood tests. 5 Pregnancy 6 Excluded if they have any of the following conditions: history of deep vein thrombosis/stroke/coronary artery disease, breast cancer or suspected breast cancer, liver disease or impaired liver function, ovarian cancer, uterine cancer, pregnancy or suspected pregnancy, or uncontrolled hypertension.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of menstrual bleed 4 months Pictograms | — |
Secondary
| Measure | Time frame |
|---|---|
| side effect of hormone: nausea and vomiting, breast tenderness, weight gain, spotting or headache 4 months Patient reported outcome using a questionnaire interview | — |
Countries
Thailand
Contacts
Public ContactChanita Sirakulawat
Srinakarinwirot university
Outcome results
None listed