Gonorrhea Urethritis Neisseria gonorrhoeae infection Povidone-Iodine Urethral Irrigation Male Gonorrhea Antimicrobial Therapy Sexually Transmitted Infections (STIs) Clinical Trial
Conditions
Interventions
Participants will receive 20-30 ml of 2% Povidone-Iodine solution via urethral irrigation twice daily for 7 days,Participants will receive 1g of Ceftriaxone via intramuscular injection once daily for
Active Comparator Drug,Active Comparator Drug
2% Povidone-Iodine Solution,Ceftriaxone
Sponsors
The First Affiliated Hospital of Gannan Medical University
Eligibility
Sex/Gender
Male
Age
15 Years to 60 Years
Inclusion criteria
Inclusion criteria: Adult male patients diagnosed with gonorrhea through NAATs and confirmed by urethral discharge microscopy. Age between 18 and 60 years. Ability to provide informed consent. No known allergies to iodine or povidone-iodine. No concomitant sexually transmitted infections other than gonorrhea.
Exclusion criteria
Exclusion criteria: Patients aged over 60 years. Patients with a history of allergic reactions to iodine or povidone-iodine. Concomitant infections with Chlamydia, Mycoplasma, or other sexually transmitted infections. Presence of urinary tract anomalies such as urethral strictures or hypospadias. History of antibiotic treatment for gonorrhea within the last 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom Relief Time Day 3 and Day 7 after treatment initiation Time (in days) until significant relief of symptoms such as pain during urination and discharge, measured through patient self-report and clinical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| NAATs Negative Conversion Rate Day 7 after treatment initiation Proportion of patients with a negative Nucleic Acid Amplification Test (NAATs) result for Neisseria gonorrhoeae | — |
Countries
China
Contacts
Public ContactMin Liu
Gannan Medical University
Outcome results
None listed