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The Efficacy of Blood Flow Restriction Exercise in Enhancing Muscle Strength and Muscle Hypertrophy Post-ACL Reconstruction: A Randomized Controlled Trial

The Efficacy of Blood Flow Restriction Exercise in Enhancing Muscle Strength and Muscle Hypertrophy Post-ACL Reconstruction: A Randomized Controlled Trial

Status
Unknown
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240812002
Enrollment
22
Registered
2024-08-12
Start date
2025-01-07
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle atrophy and decreased muscle strength after anterior cruciate ligament reconstruction ACL reconstruction Muscle strength Muscle hypertrophy Blood flow restriction exercise Low load exercise Post ACL reconstruction rehabilitation

Interventions

apply blood flow restriction exercise in addition to standard protocol for 10 minutes per time and two times per week, follow up 12 weeks,standard rehabilitation protocol 30 minutes per time, 2 times
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
Blood flow restriction training,Standard rehabilitation protocol

Sponsors

Bangkok Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1. Patients with ACL injury confirmed via clinical examination and MRI and planned for ACL reconstruction surgery in Bangkok Academy of Sports and Exercise Medicine (BASEM), Bangkok Hospital from September 2024 to April 2025 2. Age between 18 and 59 years

Exclusion criteria

Exclusion criteria: 1. Multiligament injuries of knee 2. Preexisting condition of knee causing limited rehabilitation e.g. knee stiffness, leg muscle weakness 3. Comorbidities affecting rehabilitation 4. History of venous thromoembolism or vascular disease in any lower limb 5. History of central or peripheral neurologic impairment 6. Exertional compartment syndrome 7. Patients with previous surgeries on injured knee 8. Infections in operated region 9. Perioperative or postoperative abnormal conditions such as leg swelling 10. Uncontrolled hypertension or diabetes

Design outcomes

Primary

MeasureTime frame
Muscle strength 12 weeks kilograms

Secondary

MeasureTime frame
Muscle hypertrophy 12 weeks centimetres,Range of motion 12 weeks degrees

Countries

Thailand

Contacts

Public ContactAnchisa Leewisutthikul

Bangkok Hospital

a.leewisutthikul@gmail.com023103979

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026