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A randomized, non-inferiority trial of the serum containing three herbal mixtures versus 5% topical minoxidil solution in the treatment of early stage of male androgenetic alopecia and female pattern hair loss

A randomized, non-inferiority trial of the serum containing three herbal mixtures versus 5% topical minoxidil solution in the treatment of early stage of male androgenetic alopecia and female pattern hair loss

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240810005
Enrollment
160
Registered
2024-08-10
Start date
2024-07-31
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male and female patients diagnosed with androgenic alopecia three herbal mixtures hair serum, hair thining, androgenic alopecia, minoxidil

Interventions

The study product containing a mixture of three herbs consists of three natural extracts: Phyllanthus emblica (Indian gooseberry), Thunbergia laurifolia (blue trumpet vine), and Citrus hystrix (kaffir
Study product,Minoxidil

Sponsors

Chanat Kumtornrut
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Male and female patients diagnosed with androgenic alopecia. 2. Aged 18-65 years. 3. The stages of androgenic alopecia in males, according to the revised Hamilton's classification, are at levels II, III, III vertex, or IV. The stages of androgenic alopecia in females, according to the Savin scale, are at levels I-2, I-3, I-4, or II-1.

Exclusion criteria

Exclusion criteria: 1. Participants with other hair or scalp diseases, such as seborrheic dermatitis, scalp psoriasis, scalp fungal infections, telogen effluvium, or scarring alopecia. 2. Participants with medical conditions or chronic illnesses that cause hair loss, such as cancer, anemia, thyroid hormone abnormalities, immunodeficiency, or connective tissue diseases. 3. Participants who have undergone hair transplant surgery. 4. Participants who need to use androgen hormones or anti-androgen medications, such as spironolactone, or use hormonal medications for contraception or hormone regulation. 5. Participants who are pregnant or breastfeeding. 6. Participants with a history of allergy to minoxidil or any other components in the topical minoxidil solution.

Design outcomes

Primary

MeasureTime frame
Hair density baseline, week6, week 12, week 24 by fotofinder dermoscope (Total hair counts, teminal hair counts, vellus hair counts))

Secondary

MeasureTime frame
global photographic evaluation baseline, week6, week 12, week 24 the standardized 7-point rating score using scalp photographs from -3; significant disease progression to +3; significant improvement.,hair growth questionnaire baseline, week6, week 12, week 24 growth of hair, amount of noticeable new hair, visibility of the scalp, rate of hair loss

Countries

Thailand

Contacts

Public ContactChanat Kumtornrut

Faculty of Medicine, Chulalongkorn University

chanat_1@yahoo.com6622564253

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026