Hemodynamic impacts of noninvasive ventilation Noninvasive ventilation Hemodynamic impacts Very preterm infant
Conditions
Interventions
Use Servo-n ventilator with pressure control mode in noninvasive mode. The initial setting : PIP 15-20 cmH2O, PEEP( from recent CPAP setting +/-1), inspiratory time 0.45-0.55 s, rate 20-40/min,Use Se
Experimental Device,Experimental Device
NS-NIPPPV,S-NIPPV
Sponsors
Routine To Research(R2R), Siriraj
Eligibility
Sex/Gender
All
Age
72 Hours to 14 Days
Inclusion criteria
Inclusion criteria: 1. Newborn infant with gestational age less than 32 weeks or body weight less than 1500 grams 2. Age between 72 hours and 14 days 3. Requiring nasal CPAP 4. Clinical stable
Exclusion criteria
Exclusion criteria: 1. Life-threatening anomalies such as Trisomy 13, Trisomy 18, Trisomy 21 2. Severe congenital neurological abnormality 3. Critical congenital heart disease except patent ductus arterioles, atrial septal defect
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left and right ventricular cardiac output after 2 hours of each modes of noninvasive ventilation Left and right ventricular output by echocardiogram | — |
Secondary
| Measure | Time frame |
|---|---|
| Right ventricular function after 2 hours of each modes of noninvasive ventilation tricuspid annular plane systolic excursion; TAPSE, fractional area change; FAC, tissue doppler imaging at free wall of right ventricle) | — |
Countries
Thailand
Contacts
Public ContactPunnanee Wutthigste
Mahidol university
Outcome results
None listed