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Exploring Factors Associated with Intolerance of Helmet Non Invasive Ventilation in High-Risk Postextubation Patients; A Retrospective Cohort Study

Exploring Factors Associated with Intolerance of Helmet Noninvasive Ventilation in High-Risk Postextubation Patients; A Retrospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20240731006
Enrollment
57
Registered
2024-07-31
Start date
2022-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

we would like to assess factors associated with helmet NIV intolerance during helmet NIV use in postextubation phase in patients at risk for extubation failure. Helmet NIV, NIV intolerance, high-risk extubation failure, extubation success

Interventions

Patients who received helmet noninvasive ventilation(NIV) use after postextubation period and can tolerate the device as the protocol for at least 24 hours,Patients who received helmet noninvasive ven
Other,Other
Helmet noninvasive ventilation(NIV) tolerance,Helmet noninvasive ventilation(NIV) intolerance

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over the age of 18 who had been on invasive mechanical ventilation in the medicine ICU and general ward for at least 48 hours and were considered ready for extubation after a successful spontaneous breathing trial with pressure support (PSV) mode were eligible if they were at high risk of extubation failure as defined by the following criteria: older than 65 years, those with preexisting chronic cardiac or lung disease, those with an APACHE II score of more than 12, those with a BMI of more than 30 kg/m2, those with difficult or prolonged breathing for more than seven days, and those with a Charlson Comorbidity Index greater than two on the day of extubation. Preexisting cardiac disease included left ventricular dysfunction, defined by a left ventricular ejection fraction (LVEF) equal to or below 45% from any causes; a history of cardiogenic pulmonary edema; documented ischemic heart disease; or permanent atrial fibrillation. Chronic obstructive pulmonary disease, obesity hypoventilation syndrome, and restrictive lung disease were identified as preexisting chronic pulmonary diseases which we analyzed data from patient who did not tolerate with helmet NIV.

Exclusion criteria

Exclusion criteria: Patients with long-term NIV use, neuromuscular disease (i.e., myopathy or myasthenia gravis), traumatic brain injury leading to intubation, accidental or self-extubation, and do-not-resuscitation after extubation, and having contraindications to NIV use

Design outcomes

Primary

MeasureTime frame
factor associated helmet noninvasive ventilation (NIV) intolerance within 24 hours after extubation patient who cannot tolerate device for 24 hours

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Thailand

Contacts

Public ContactNapat Jirawat

Faculty of Medicine Vajira Hospital, Nawamindradhiraj University

aussie_aun@hotmail.com0893291969

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026