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Effect of gum chewing on gastrointestinal function after complete surgical staging in gynecologic malignancies : a randomized controlled trial

Effect of gum chewing on gastrointestinal function after complete surgical staging in gynecologic malignancies : a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240730002
Enrollment
68
Registered
2024-07-30
Start date
2024-07-30
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative bowel ileus in complete staging surgery in gynecologic malignancies chewing gum complete staging surgery gynecologic malignancies Postoperative bowel ileus gastrointestinal mobility gastrointestinal function

Interventions

Group A will receive the chewing sugar-free gum (Xylitol) the next day after surgery every 4 hours. Continuous chewing one piece of gum lasts for 15 minutes by continuous natural rhythm chewing of pa

Sponsors

Khon Kaen hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients aged 18 years old or more 2.Female undergoing complete surgical staging in gynecologic malignancies which are endometrial cancer, ovarian cancer and other e.g. peritoneal cancer (Total abdominal hysterectomy with bilateral salpingo-oophorectomy with bilateral pelvic lymph node dissection with omentectomy with peritoneal washing with or without paraaortic dissection with or without peritoneal biopsy) 3.Good consciousness 4.Patient who can communicate in Thai fluently

Exclusion criteria

Exclusion criteria: 1.Patients who are unable to chew, on removable dental prostheses, severe dental caries, or severe loose teeth 2.Mint allergy 3.Xylitol allergy 4.Poor Cognitive function 5.Risk of choking or dysphagia 6.Major bowel surgery e.g. history of end to end anastomosis bowel, colostomy 7.Chronic diseases requiring anti-cholinergic drugs for treatment e.g. chronic 8.bstructive pulmonary disease, Parkinson disease, irritable bowel syndrome and psychiatric disorder 9.Need of intensive care unit

Design outcomes

Primary

MeasureTime frame
duration of first flatus duration from the end of surgery to time of passing first flatus time (hours)

Secondary

MeasureTime frame
duration of first defecation duration from the end of surgery to time of passing first flatus time (hours),post-operative nausea from the end of surgery until discharge n (%),post-operative vomiting from the end of surgery until discharge n (%),Additional analgesics from the end of surgery until discharge n (%),Additional anti- emetic from the end of surgery until discharge n (%)

Countries

Thailand

Contacts

Public ContactPattarapapa Tomuen

Khon Kaen hospital

patarapapa.gtxre1@gmail.com0885630157

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026