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Simple Neurectomy Versus Neurectomy with Intramuscular Implantation for Interdigital Neuroma: A randomized controlled trial

Simple Neurectomy Versus Neurectomy with Intramuscular Implantation for Interdigital Neuroma: A randomized controlled trial

Status
Unknown
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240724001
Enrollment
30
Registered
2024-07-24
Start date
2023-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interdigital neuritis Morton Neuroma

Interventions

Once the common digital nerve was cut sharply just distal to the bifurcation, it was transplanted into intrinsic foot muscle.,The proper interdigital nerves were transected just distal to the bifurcat
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
Neurectomy with intramuscular transplantation,Simple neurectomy

Sponsors

Phramongkutklao Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age 20 years or older., 2. Able to communicate in Thai or English., 3. Diagnosed with interdigital neuritis in a single web space based on tenderness location and/or Mulder's click during physical examination, MRI findings, and/or positive diagnostic injection at the affected web space., 4.No response to conservative treatment for at least 6 months.

Exclusion criteria

Exclusion criteria: 1. History of previous surgery for interdigital neuroma/neuritis., 2.Presence of multiple interdigital neuromas in the same foot. History of previous forefoot surgery.,3.Diagnosis of polyneuropathy.4.Poorly controlled diabetes mellitus with neuropathy.,5.Established proximal nerve root pathology (e.g., lumbar radiculopathy).6.Presence of another neoplasm in the same web space.7.Metatarsalgia of undetermined cause.8.Inability to comprehend or communicate about the study protocol and treatment due to physical or mental reasons.9.Pregnancy.10.Patients with other contraindications to surgery.

Design outcomes

Primary

MeasureTime frame
Pain (Metatarsalgia) at 12 months after intervention pain visual analogue scale

Secondary

MeasureTime frame
Foot function at 12 months after intervention Foot and ankle ability measure (FAAM) score,Quality of life at 12 months after intervention SF-36

Countries

Thailand

Contacts

Public ContactChamnanni Rungprai

Phramongkutklao Hospital

chamnanni@yahoo.com023547600

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026