post-operative tonsillectomy pain and wound healing tonsillectomy, lysozyme chloride
Conditions
Interventions
lysozyme chloride 30 mg 1 tab bid po pc,Placebo 1 tab bid po pc
Experimental Drug,Placebo Comparator Drug
lysozyme chloride,Placebo (lactose monohydrate, microcrystalline cellulose, polyvinyl-pyrrolidone K-30, talcum and magnesium stearate)
Sponsors
Choomit 1967 Co., Ltd.
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-65 years 2.The participants must have met the indication for tonsillectomy
Exclusion criteria
Exclusion criteria: 1. The participants have contraindication for surgery such as take antiplatelet medication or bleeding condition from genetic disease 2. Have contraindication for general anesthesia 3. Have underlying disease that reduce wound healing 4. Have history of RT/CCRT 5. Using steroid or immunotherapy drug 6. The participants have contraindication for acetaminophen, ibuprofen 7. The participants have contraindication for lysozyme chloride and egg white 8. Pregnancy of Lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing 1,2,3,7,14 days Percent of epithelialization of tonsillar bed | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain 1,2,3,7,14 days Pain score by visual analog scale | — |
Countries
Thailand
Contacts
Public ContactPanuwat Wongwattana
Srinakharinwirot University
Outcome results
None listed