patients with facial wrinkle wrinkle, Skin rejuvenation
Conditions
Interventions
Smart minilux Combo ,Wavelength 630 +/- 10 nm ,Fluence 60 J/cm2 .,Microneedle patch consist of PMMA (Polymethylmethacrylate) ,Hieght 400 micrometers ,FDA Class I, IIA, IIB approved
Experimental Device,Experimental Device
Red LED light,Microneedle Patch
Sponsors
Bangkok Dusit Medical Services
Eligibility
Sex/Gender
All
Age
25 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1.Participants female and male with age 25 to 55 years old with modified Fitzpatrick Wrinkle Scale more than class 1 2.Pre-menopause female
Exclusion criteria
Exclusion criteria: 1. Menopause 2. Current tobacco use 3. Tattoos that cover the proposed skin surface 4. Outdoor workers and sun exposure risk 5. Any skin lesions that might affect the study results such as atopic dermatitis ,herpes simplex infection, history of active or systemic infection, history of hypertrophic scar, eczema or sunburn in the area 6. Any history of adverse effects of polymethylmethacrylate (PMMA) 7. Have done Neuromodulators treatment (Botulinum toxins injections) within 6 months 8. Have done Filler injections in the nasolabial fold and periorbital within 1 year 9. Use of energy-based devices within 1 year 10. Have done Mesotherapy injections within 1 month 11. Have done Biostimulator injection within 6 months 12. Have done any sort of energy-based device within 1 year 13. Have done any sort of LASERs or skin resurface procedures within 1 months 14. Underlying with Photosensitivity condition including Porphyria, Lupus erythematosus, Rosacea, Solar urticaria 15. Underlying with bleeding diseases 16. Currently on Vitamin A derivatives, anticoagulants 17. Pregnant or on Lactation 18. Daily use anti-wrinkles facial cream and/or lotion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin rejuvination at 4 months after start of the intervention Modified Fitzpatrick Wrinkle Scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety 2 week after every intervention Physician and Patient reported outcome using a questionnaire interview | — |
Countries
Thailand
Contacts
Public ContactWatcharakorn Rattanakan
Thammasat university
Outcome results
None listed