Cirrhosis Hepatocellular carcinoma Esophageal varices Portal hypertension Cirrhosis Hepatocellular carcinoma Esophageal varices Portal hypertension
Conditions
Interventions
Hepatocellular carcinoma and cirrhosis patients,Hepatocellular carcinoma and cirrhosis patients
Diagnostic,Diagnostic
Standard test/diagnostic criteria (EGD) for outcome (Varices),Alternative test/criteria (Spleen stiffness)
Sponsors
Khon Kaen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patient with liver cirrhosis Patient with hepatocellular carcinoma
Exclusion criteria
Exclusion criteria: History of decompensated cirrhosis Morbid obesity (BMI > 35 kg/m2) Splenectomy Splenic lesion (splenic mass/abscess) Pacemaker or cardiac defibrillator implant patient Known or suspect malignancy other than HCC History of esophageal varices History of Endoscopic variceal ligation History of TIPS Portal hypertension that not caused by cirrhosis and HCC Hematologic disease with splenomegaly Previous non-selective beta-blocker Pregnancy or breast feeding Severe infection Heart disease (NYHA functional class III,IV) COPD GOLD C or D Chronic kidney disease stage IV, V
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Esophageal varices within 1 month after or before spleen stiffness measurement EGD | — |
Secondary
| Measure | Time frame |
|---|---|
| Spleen stiffness within 1 month after or before EGD Spleen stiffness measurement | — |
Countries
Thailand
Contacts
Public ContactBenjaphol Panyapornsakul
Internal medicine department, Khon Kaen University
Outcome results
None listed