Distal radius fracture Hypovitaminosis D Elder Distal radius fracture Distal radius fixation Vitamin D supplementation
Conditions
Interventions
60,000 IU/week (on monday, thursday, saturday) with oral administration for 6 months,-
Active Comparator Drug,Placebo Comparator No treatment
Vitamin D2 (Ergocalciferol),placebo
Sponsors
Siriraj hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients older than 60 years. 2. Have a distal radius fracture from a low-energy trauma and received surgical treatment using ORIF (Open Reduction and Internal Fixation) with plate and screws within 21 days post-injury.
Exclusion criteria
Exclusion criteria: 1. History of receiving vitamin D within the past 6 months 2. Inflammatory joint diseases such as RA, SLE, or Gout 3. Abnormalities in bone metabolism, such as CKD beyond stage IV 4. Diagnosed with neuromuscular or neurosensory conditions affecting wrist function 5. History of using steroids within the past 12 months 6. History of injury or fracture or surgery in both wrists 7. Hand disease from both congenital and acquired in both wrists 8. Cognitive impairment 9. History of severe allergic reactions to vitamin D supplements
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hand grip strength recovery at 6 months after surgery Jamar dynamometer | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional score 1 week, 6 week, 3 months, 6 months, 1 year Thai version of Patient-Rated Wrist Evaluation,Appendicular skeletal mass index (ASMI) 1 week, 6 week, 3 months, 6 months, 1 year dual-frequency bioelectrical impedance analysis,Vitamin D level 6 months electrochemiluminescence (ECL) binding assay,Radiographic alignment 1 week, 6 week, 3 months, 6 months, 1 year Intelli-Space PACS Enterprise (Philips) | — |
Countries
Thailand
Contacts
Public ContactKittipich Sangkamard
Mahidol university
Outcome results
None listed