who have sleep problems, can'
Conditions
Interventions
4 capsule ac. (4 capsule Placebo)
4 capsule hs. (lorazepam (0.5) 1 capsule + 3 capsule placebo),4*2 ac. + hs. (500 mg/capsule)
Active Comparator Drug,Experimental Drug
lorazepam,Pom-lueng fever recipe
Sponsors
Department of Thai Traditional and Alternative Medicine
Eligibility
Sex/Gender
All
Age
32 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. male or female with 32-60 year 2. who have sleep problems, can't sleep, can't sleep well. and has been awake while sleeping for at least 1 month with a PSQI score of more than 5 points. 3. eGFR > 60 mL/min AST < 105, ALT < 150 Hb > 10 g/dL 4. women with negative urine pregnancy test 5. Be voluntary and willing to participate in the project Along with signing the consent form to participate.
Exclusion criteria
Exclusion criteria: 1. abnormal liver and kidnye 2. Patients with cardiovascular disease High blood pressure, GERD, taking anticoagulants/warfarin/aspirin/clopidogrel/and Blood pressure medicine 3. patient use Phenytoin, Propranolol, Theophylline or Rifampicin 4. Have a history of allergic reactions to herbal medicines People who have used during 2 weeks herbs that contain cannabis herbs or other herbs that affect sleep 5. Other procedures that affect sleep, such as acupuncture or other treatments. 6. People who drank alcohol in the 1 month before joining the project and while participating in the project 7. People with a history of drug use 8. Pregnant woman breastfeeding woman
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sleep quality at 1 months after end of the intervention Pittsburgh sleep Quality Index (PSQI) | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life at 1 months after end of the intervention Thai Pictorial Quality of lift: PTQL,stress at 1 months after end of the intervention ST-5: Stress Test Questionnaire,side effect at 1 months after end of the intervention labatory (CBC, Bun, Cr, LFT, Uric acid, Lipid profile, EKG)) | — |
Countries
Thailand
Contacts
Public Contactsurasak imiam
Prapokklao hospital
Outcome results
None listed