Xerostomia in patients with overactive &
Conditions
Interventions
Anthocyanins extracted from Oryza sativa was produced in topical tablet form for relieving xerostomia symptoms,Placebo arm
Active Comparator Drug,Placebo Comparator Drug
Topical sialogogue,Placebo
Sponsors
Faculty of medicine Ramathibodi Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Overactive bladder and neurogenic bladder patient who use anticholinergic drug with xerostomia symptoms Age 18 year old or older Informed consent was made
Exclusion criteria
Exclusion criteria: Recently xerostomia symptoms within 3 months History of head & neck radiation Autoimmune disease History of salivary gland surgery Dental and oral infection Uncooperative patient History of drug allergy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Xerostomia symptoms 1 month Subjective dry mouth VAS | — |
Secondary
| Measure | Time frame |
|---|---|
| Stimulated salivary flow rate 1 month Prohibited from eating and drinking for 60 mins before saliva collection. They chewed a paraffin cube for 30 seconds, then spit into a tube for 5 mis, after which the saliva volume was measured. | — |
Countries
Thailand
Contacts
Public ContactSurawach Piyawannarat
Faculty of medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed