Enrolled the healthy patient who need to extract the single-tooth extraction in the premolar tooth due to unrestorable (caries, fracture, or orthodontic treatment) with an intact buccal bone plate (more than 50%) Alveolar ridge preservation, rhBMP-2, Collagen.
Conditions
Interventions
Local anesthesia (2% lidocaine with epinephrine 1:105 in a quantity, 1-2 cartridges), was administered, and the tooth was atraumatic extracted. The extraction wound was cleaned with 0.9% NSS. In the e
Ethicon, Norderstedt, Germany). Both groups followed the same postoperative care regimen: postoperative antibiotics (amoxicillin 500 mg) were prescribed every 8 hours for 5 days and ibuprofen 400 mg
Experimental Drug,No Intervention No treatment
Absorbable collagen sponge(ACS)/rhBMP-2,No treatment/ Standard of care
Sponsors
Thailand Science Research and Innovation (TSRI), and National Science, Research and Innovation Fund (NSRF)
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: The healthy patient who need to extract the single-tooth extraction in the premolar tooth due to unrestorable (caries, fracture, or orthodontic treatment) with an intact buccal bone plate (more than 50% Healthy adults patient (20 years or older) and able to sign an informed consent form. All extraction sites have a keratinized gingival tissue in a minimum width of 2 mm
Exclusion criteria
Exclusion criteria: Presence of periodontal disease. History of smoking, radiotherapy, or chemotherapy within the past 5 years Pregnancy or breastfeeding. Previous or current medication e.g. steroids, antiresorptive drugs including affecting on bone remodelling phase. General contraindications for surgical treatment including antiplatelet or anticoagulation drugs. Allergy to collagen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone reduction 12 weeks Mean difference bone reduction | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical evaluation 12 weeks Soft tissue healing | — |
Countries
Thailand
Contacts
Public ContactPawornwan Rittipakorn
Suranaree University of Technology
Outcome results
None listed