Skip to content

Efficacy of 1% permethrin lotion in treatment of head lice infestations in primary school children in Thailand

Efficacy of 1% permethrin lotion in treatment of head lice infestations : A clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240715005
Enrollment
73
Registered
2024-07-15
Start date
2021-11-24
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male and female schoolchildren aged 6 to 13, with head lice infestations. Pediculus humanus capitis, head lice infestations, kdr mutation, permethrin lotion

Interventions

The medication used for the treatment was permethrin 1% lotion. The medication application method was advised as the following: Apply the lotion to dry hair, the scalp, behind the ears, and the nape o
Experimental Drug
1% permethrin lotion

Sponsors

Fundamental Fund, Thailand Science Research and Innovation (TSRI)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 13 Years

Inclusion criteria

Inclusion criteria: Male and female schoolchildren aged 6 to 13, with at least one live head louse identified through the dry combing method.

Exclusion criteria

Exclusion criteria: Patients with a history of allergy to permethrins, pyrethroids, pyrethrins, or chrysanthemum, coexisting scalp diseases and disorders, use of any pediculicide-based products or medication within the last two weeks, non-adherence to the protocol, or refusal to complete informed consent.

Design outcomes

Primary

MeasureTime frame
Free from head lice (cure) 7 and 14 days after first treatment no living lice,kdr mutation before treatment PCR-RFLP

Secondary

MeasureTime frame
Adverse events 7 and 14 days after first treatment pruritus and burning score

Countries

Thailand

Contacts

Public ContactNarisa Brownell

Chulalongkorn University

Narisa.br@chula.ac.th022564387

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026