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Safety evaluation and clinical anticandidal and antibacterial efficacy of coconut oil mouthwash formulation in older adults.

Safety evaluation and clinical anticandidal and antibacterial efficacy of coconut oil mouthwash formulation in older adults.

Status
Unknown
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240711004
Enrollment
60
Registered
2024-07-11
Start date
2024-04-29
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Candida and bacterial counts in older adults candida ,bacterial, oral rinse , virgin coconut oil

Interventions

rinse 2 times per day after brushing, gargle for 5 minutes.,rinse 2 times per day after brushing, gargle for 30 seconds.,rinse 2 times per day after brushing, gargle for 30 seconds.
Virgin coconut oil mouthwash formulation,Chlorhexidine mouthwash,Normal saline

Sponsors

Faculty of Dentistry, Chiangmai University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged 60 years and older, classified as ASA (American Society of Anesthesiologists) 1-3. 2. Independent older adults who can perform oral rinsing independently. 3. Candida spp. found through concentrated oral rinse culture, with a quantity not exceeding 600 cfu/ml

Exclusion criteria

Exclusion criteria: 1. History of allergy to coconut oil, chlorhexidine mouthwash, or other components used in this research. 2. Symptoms of oral candidiasis 3. Smokers or quit smoking less than 1 year ago. 4. Experiences difficulty swallowing (dysphagia). 5. Cognitive impairment and abnormal brain function affecting communication and cooperation. History of using specific or systemic antifungal medications within 1 month before participating in the research. 6. Not willing to participate in the research project.

Design outcomes

Primary

MeasureTime frame
Reduction in the quantity of Candida and overall bacteria. at 2 weeks after the intervention CFU/ml

Secondary

MeasureTime frame
Patients' satisfaction at 2 weeks after the intervention Patient reported outcome using a questionnaire interview

Countries

Thailand

Contacts

Public ContactDarunee Owittayakul

Faculty of dentistry ,Chiangmai University

jeeleeja@gmail.com0818827700

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026