Smokers cytisine, Smokers , Smoking Cessation
Conditions
Interventions
Cytisine 1.5 mg each, Film-coated tablets, take 2 tablets 3 times a day for 25 days.
The smoker should gradually Reduce the amount of smoking during the first 4 days of taking the medicine. And stop s
Experimental Drug,Experimental Drug
Simplified TID Regimen,Downward Titration regimen
Sponsors
Thai Health Promotion Foundation
The Pharmacy Council of Thailand.
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Over 18 years of age and not over 65 years of age. 2. Current daily cigarette smokers. There is a need to quit smoking at the preparation/contemplation level according to The Trans theoretical Model. 3. Sign the Informed Consent Form. 4. Smoke more than 10 cigarettes per day. 5. If you are a woman of reproductive age and have a chance of becoming pregnant Must be willing to use birth control before participating in the research project. 6. Have a mobile phone that can set reminders and allow the use of telephone reminder methods. For use in evaluating drug compliance of volunteers
Exclusion criteria
Exclusion criteria: 1. Have a congenital disease that may be dangerous from receiving research drugs, such as heart arrhythmia. Coronary artery disease, cancer, chronic kidney disease (creatinine clearance <30 ml/minute), psychiatric disorders such as depression. schizophrenia or patients who also use other types of drugs such as marijuana, amphetamines, etc. 2. Are pregnant or breastfeeding 3. Already being treated with medications to help you quit smoking, including nicotine replacement therapy (NRT), Nortriptyline, Bupropion, Clonidine, and Varenicline.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| continuous smoking abstinence at weeks 4 and 12 verified by self reporting and exhaled carbon monoxide levels at 12 weeks after end of the intervention exhaled carbon monoxide levels (less than7 ppm). | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse reactions at 12 weeks after end of the intervention Patient reported outcome using a questionnaire interview | — |
Countries
Thailand
Contacts
Public ContactNuttaya Panichdee
Department of Medicine, Kalasin Hospital
Outcome results
None listed