The effect of gait innovation, Transcranial Magnetic Stimulation on Electroencephalogram and Blood chemical in Osteoarthritis of Knee condition

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20240710003

Enrollment

Registered

2024-07-10

Start date

2024-01-30

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee pain difficult to perform ADL muscle weakness poor Balance poor Cardiopulmonary system impair cognitive osteoarthritis of knee: OA knee Brainwave Muscle morphology muscle strengthening 5. Balance 6. Cardiopulmonary system 7.cognitive

Interventions

Normal ADL,Normal ADL,Normal ADL with walking device ,Normal ADL with received transcranial electrical stimulation for for 20 mins/time 3 times/weak total 36 times ,Normal ADL with received transcra

No Intervention No treatment,No Intervention No treatment,Experimental Device,Experimental Other,Experimental Other

Control group healthy ,knee osteoarthritis who did not receive treatment.,knee osteoarthritis who used assistive walking devices.,knee osteoarthritis who received transcranial electrical stimulation.,

Eligibility

Sex/Gender

All

Age

45 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Knee pain for more than 6 months. 2. Pain occurs more than 3 days per week. 3. No joint deformities and no abnormalities in the range of motion. 4. No intake of antioxidant supplements or vitamins for at least 3 months.

Exclusion criteria

Exclusion criteria: 1. Individuals with knee pain for more than 6 months. 2 Individuals diagnosed with epilepsy. 3. Individuals who regularly take pain relief medication.

Design outcomes

Primary

Measure	Time frame
brain wave 20 mins Electroencephalography,ultrasound imagines 5 mins ultrasound imagine ,Balance 10 mins (Postural sway): Biometric Elink model EP40 system, ,10 meter walk test 5 mins time of walk within 10 Meters,6 minute walk test 6 mins distance of walk within 6 mins,Balance 5 mins Mini-Balance Evaluation Systems (TestMini-BESTest),muscle strength 10 mins Biodex model System 4 Pro,cognitive 10 mins Electroencephalography, P300 wave (P300),Levels of memory-related chemicals, antioxidants, oxidative stress, distribution of APO E genotype, GPX polymorphism, and BDNF. 10 mins Blood detects	—

Measure

Time frame

brain wave 20 mins Electroencephalography,ultrasound imagines 5 mins ultrasound imagine ,Balance 10 mins (Postural sway): Biometric Elink model EP40 system, ,10 meter walk test 5 mins time of walk within 10 Meters,6 minute walk test 6 mins distance of walk within 6 mins,Balance 5 mins Mini-Balance Evaluation Systems (TestMini-BESTest),muscle strength 10 mins Biodex model System 4 Pro,cognitive 10 mins Electroencephalography, P300 wave (P300),Levels of memory-related chemicals, antioxidants, oxidative stress, distribution of APO E genotype, GPX polymorphism, and BDNF. 10 mins Blood detects

—

Secondary

Measure	Time frame
memory function 10 mins the Digit Span Forward test (DSF) and the Digit Span Backward test (DSB),%body fat 5 mins skin fold caliper,Functional 10 mins Modified total Western Ontario and McMaster Universities Arthritis Index (WOMAC) Scale in Thai	—

Countries

Thailand

Contacts

Public ContactNongnuch Luangpon

Allied health Sciences, Burapha university

nongnuchl@go.buu.ac.th0845454463

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026