Using Computer-Aided polyp detection system (CADe) to maintain the high quality in adenoma detection rate during community-based colorectal cancer screening in Thailand: A randomized trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20240710001

Enrollment

500

Registered

2024-07-10

Start date

2023-05-10

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Due to limited endoscopy resources and personnel in Thailand, a high-volume colonoscopy (50-100 colonoscopies/day) performed within a few days by a group of community endoscopists gathering from different centers has been utilized to clear stranded patients with FIT positive especially after COVID-19 pandemic. Because of the rush in procedure time to achieve a high turnover rate ( more than 15 colonoscopies/endoscopist/day), these endoscopists may develop fatigue. This in turn may contribute to

Interventions

Computer-aided polyp detection(CADe) system for improving of adenoma detection rate during colorectal cancer screening(colonoscopy),White light endoscopy group or control group as standard of care dur

Active Comparator Device,Placebo Comparator Device

CADe group,White light endoscopy group

Eligibility

Sex/Gender

All

Age

50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. All participants with age 50-75 years

Exclusion criteria

Exclusion criteria: 1. Genetic disorders increasing colon cancer risk, such as familial adenomatous polyposis, Lynch syndrome, or past colon cancer. 2. Inflammatory bowel disease (IBD). 3. History of colon surgery. 4. Abnormal symptoms: bloody stools, alternating constipation and diarrhea, unexplained anemia, or weight loss.

Design outcomes

Primary

Measure	Time frame
ADR 2 weeks after colonoscopy and pathology reported Adenoma detection rate is percentage of patients undergoing screening colonoscopy, who have one or more precancerous polyps detected.	—

Secondary

Measure	Time frame
proximal adenoma detection rate (pADR), advanced adenoma detection rate (AADR), and the number of adenomas/proximal adenomas/advanced adenomas per colonoscopy (APC, pAPC, and AAPC, respectively) 2 weeks after colonoscopy and pathology reported pADR is ADR that adenoma detected proximal to the splenic flexure. AADR is ADR with adenoma larger than 10 mm in size or with high-grade dysplasia.APC is number of adenomas detected per colonoscopy.	—

Measure

Time frame

proximal adenoma detection rate (pADR), advanced adenoma detection rate (AADR), and the number of adenomas/proximal adenomas/advanced adenomas per colonoscopy (APC, pAPC, and AAPC, respectively) 2 weeks after colonoscopy and pathology reported pADR is ADR that adenoma detected proximal to the splenic flexure. AADR is ADR with adenoma larger than 10 mm in size or with high-grade dysplasia.APC is number of adenomas detected per colonoscopy.

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Countries

Thailand

Contacts

Public ContactSittikorn Linlawan

Phrachomklao Hospital, Phetchaburi Province

sittilin@yahoo.com032709999

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026