early childhood caries prevention Silver diamine fluoride, Fluoride varnish, early childhood caries, plaque fluoride, salivary fluoride
Conditions
Interventions
38% silver diamine fluoride (38% SDF
44,800 ppm fluoride) is a topical fluoride. It contains high fluoride concentrations that promote remineralization of both enamel and dentine caries, have an antimicrobial effect from the silver conte
22,600 ppm fluoride) and is recommended for application in children at high risk of caries, primarily for preventing and arresting the progression of enamel caries.It has been commonly used due to its
Silver Diamine Fluoride (SDF),Fluoride varnish (FV),Silver Diamine Fluoride combined with Fluoride varnish
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
3 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. Healthy and cooperative children aged 3-6 years old. 2. Children who have a full primary dentition, consisting of 20 primary teeth. 3. Children who have at least 1 tooth with dentinal caries.
Exclusion criteria
Exclusion criteria: 1. Children who have sound non carious teeth. 2. Children with a medical, physical, or mental disability. 3. Children with a known allergy to fluoride, silver, or colophony agents 4. Children who receiving professional fluoride treatment in the past 3 months. 5. Children who had taken long-term medications, medication influences salivary flow or taken antibiotic within one month before the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plaque and salivary fluoride level baseline, 5 minutes, 30 minutes, 60 minutes, 24 hours, 48 hours Part per million of fluoride (ppmF) | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactChavanya Asavalertpalakorn
Faculty of dentistry, Mahidol university
Outcome results
None listed