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The Role Of Serum Prolidase Activity, Matrix Metalloproteinase-1, Matrix Metalloproteinase-7, Transforming growth factor-beta Values In Prediction Of Early Fibrosis In Patients With Moderate And Severe COVID-19

The Role Of Serum Prolidase Activity, Matrix Metalloproteinase-1, Matrix Metalloproteinase-7, Transforming growth factor-beta Values In Prediction Of Early Fibrosis In Patients With Moderate And Severe COVID-19

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20240701005
Enrollment
68
Registered
2024-07-01
Start date
2022-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 Pulmonary fibrosis Post COVID-19 serum prolidase activity MMP-1 MMP-7 TGF-Beta LDH

Interventions

Patients with non-fibrotic changes after CT evaluation.,Patients with fibrotic changes after CT evaluation.
Diagnostic,Diagnostic
Group 1,Group 2

Sponsors

Selcuk University Faculty of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients aged 18 years and over who were diagnosed or considered as possible COVID-19.

Exclusion criteria

Exclusion criteria: 1. Pregnant women, 2. Patients under 18 years of age, 3. Patients with pre-existing interstitial lung disease (ILD), 4. Patients with malignancy, 5. Patients who did not sign a consent form were excluded from the study.

Design outcomes

Primary

MeasureTime frame
Fibrosis 12 weeks after fist admission. Fibrosis score—

Secondary

MeasureTime frame
Honeycomb pattern 12 weeks after fist admission. Computed Tomography—

Countries

Turkey

Contacts

Public ContactDidem Zengin

Selcuk University Medical Faculty

dr.didemzengin@gmail.com5545506310

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026