The effect of desogestrel 75 micrograms (progestogen only pills) and depot medroxyprogesterone acetate (DMPA) on bone markers in reproductive aged women desogestrel progestogen only pills depot medroxyprogesterone acetate DMPA bone markers P1NP CTX Osteocalcin
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Female age 20 to 45 years old 2. Visit gynecologist clinic at Maharaj Nakorn Chiang Mai Hospital 3. Have indication to use progestin only hormone
Exclusion criteria
Exclusion criteria: 1. Any medical condition that effects bone metabolism 2. Current medication that effects bone metabolism 3. 6 weeks postpartum or breastfeeding 4. History of abnormal bone mineral density (BMD) 5. History of hormonal drug use in 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone markers 3 months Procollagen type 1 extension peptide (P1NP), Osteocalcin (OC) and Carboxy-terminal collagen crosslinks (CTX) | — |
Secondary
| Measure | Time frame |
|---|---|
| abnormal uterine bleeding 3 mo Call to in quire | — |
Countries
Thailand
Contacts
Maharaj Nakorn Chiang mai Hospital