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Comparison of the effect of desogestrel 75 micrograms (progestogen only pills) and depot medroxyprogesterone acetate (DMPA) on bone markers in reproductive aged women

Comparison of the effect of desogestrel 75 micrograms (progestogen only pills) and depot medroxyprogesterone acetate (DMPA) on bone markers in reproductive aged women, Comparative prospective cohort study

Status
Unknown
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20240628006
Enrollment
64
Registered
2024-06-28
Start date
2023-10-12
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of desogestrel 75 micrograms (progestogen only pills) and depot medroxyprogesterone acetate (DMPA) on bone markers in reproductive aged women desogestrel progestogen only pills depot medroxyprogesterone acetate DMPA bone markers P1NP CTX Osteocalcin

Interventions

Patients with indicated to use progestin only hormone and choose desogestrel 75 micrograms oral once daily,Patients with indicated to use progestin only hormone and choose depot medroxyprogesterone ac
Treatment,Treatment
Desogestrel,DMPA

Sponsors

Chiang Mai University, Thailand
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Female age 20 to 45 years old 2. Visit gynecologist clinic at Maharaj Nakorn Chiang Mai Hospital 3. Have indication to use progestin only hormone

Exclusion criteria

Exclusion criteria: 1. Any medical condition that effects bone metabolism 2. Current medication that effects bone metabolism 3. 6 weeks postpartum or breastfeeding 4. History of abnormal bone mineral density (BMD) 5. History of hormonal drug use in 3 months

Design outcomes

Primary

MeasureTime frame
Bone markers 3 months Procollagen type 1 extension peptide (P1NP), Osteocalcin (OC) and Carboxy-terminal collagen crosslinks (CTX)

Secondary

MeasureTime frame
abnormal uterine bleeding 3 mo Call to in quire

Countries

Thailand

Contacts

Public ContactTanapak Wisetmongkolchai

Maharaj Nakorn Chiang mai Hospital

t.wisetmongkolchai@gmail.com053935829

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026