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Comparison of postoperative dysphagia between local 80 vs 40 mg methyprednisolone application following multilevel anterior cervical discectomy and fusion : a double-blinded, prospective, randomized controlled trial

Comparison of postoperative dysphagia between local 80 vs 40 mg methyprednisolone application following multilevel anterior cervical discectomy and fusion : a double-blinded, prospective, randomized controlled trial

Status
Unknown
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240627005
Enrollment
60
Registered
2024-06-27
Start date
2022-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CSM CSR postoperative dysphagia CSM CSR postoperative dysphagia

Interventions

80 mg of methyprednisolone was diluted with NSS 1ml then mixed with gelatin matrix which placed at retropharyngeal area,40 mg of methyprednisolone was diluted with NSS 2ml then mixed with gelatin matr
Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery
80 mg of methyprednisolone,40 mg of methyprednisolone

Sponsors

maharat nakhon ratchasima hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: CSM CSR PATIENT WHO UNDERGO >= 2 LEVEL OF ACDF WITH PLATING OPERATION AGE MORE THAN 20 YEARS OLD

Exclusion criteria

Exclusion criteria: INFLAMMATORY DISEASE EX. RA, AS ANY OPERATION FOR TRAUMA ANY INFECTION PRIOR STEROID USED EAT-10 SCORE >= 3 PREOP DENIED TO ENROLLED THIS STUDY

Design outcomes

Primary

MeasureTime frame
Dysphagia rate Postoperative day 3 , follow up 2 weeks and 6 weeks Eating Assessment tool(EAT-10) score

Secondary

MeasureTime frame
disability point in patients with neck pain Postoperative day 3 , follow up 2 weeks and 6 weeks Neck disability Index

Countries

Thailand

Contacts

Public ContactNatcha Chutchomchuen

maharat nakhon ratchasima hospital

mt.porpim@gmail.com0981754056

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026