Healthy Thai children aged 1 month to not more than 5 years nasopharyngeal carriage seroprevalence pneumococcal conjugate vaccine streptococcus pneumonia antimicrobial susceptibility
Conditions
Interventions
Nasopharyngeal swab for
Experimental No treatment
Nasopharyngeal swab
Sponsors
Pediatric Infectious Disease Society of Thailand (PIDST)
Eligibility
Sex/Gender
All
Age
1 Months to 5 Years
Inclusion criteria
Inclusion criteria: 1. Male or female participants aged 1 month to not more than 5 years. 2. Participants who are in good health at the time of entry to the trial, as determined by medical history and the clinical judgment of the investigator. 3. Parents/guardians/legal representatives of the participants must provide consent and sign the informed consent form prior to the initiation of any trial procedures.
Exclusion criteria
Exclusion criteria: 1. Having a body temperature of 38 degrees Celsius (100.4 degrees Fahrenheit) or higher within 24 hours prior to enrollment in the trial. 2. Having respiratory symptoms on the day of entry to the trial. 3. Having a chronic disease that is unstable and whose symptoms cannot be controlled. 4. Having an immune deficiency or receiving immunosuppressive drugs or steroids. 5. Receiving antibiotics within 72 hours prior to enrollment in the trial. 6. Having any abnormalities or medical history that the investigator deems unsuitable for participation in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pneumococcal carriage prevalence and serotype NA real-time PCR and conventional PCR | — |
Secondary
| Measure | Time frame |
|---|---|
| Antimicrobial resistance pattern of pneumococcal colonization NA Clinical and Laboratory Standards Institute (CLSI) guidelines | — |
Countries
Thailand
Contacts
Public ContactChonnamet Techasaensiri
Ramathibodi Hospital
Outcome results
None listed