Patients with edentulism who must or mustn'
Conditions
Interventions
Patients with edentulism who mustn'
t have bone grafting for dental implant treatment ,Patients with edentulism who must have bone grafting using xenograft for dental implant treatment
Treatment,Treatment
Control,Grafting
Sponsors
Office of Research Affairs, Faculty of Dentistry, Chulalongkorn University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. In the bone grafting group, subjects must have bone grafting using xenograft. 2. All of subjects must have implant placements using The Straumann Dental Implant, Basel, Switzerland. 3. A period of at least 3 months between extraction and implant placement. 4. All of subjects must have enough excess soft tissue after implant placement that can be collected without interfering the normal treatment protocol.
Exclusion criteria
Exclusion criteria: 1. The risk factors that affect soft tissue inflammation including uncontrolled diabetes, uncontrolled periodontal disease, previously peri-implantitis, or smoking. 2. Use of antibiotics, anti-inflammatory drugs, or local antimicrobial agents within the former 6 months. 3. Subjects that do not have enough excess soft tissue after implant placement which the collecting process will interfere the normal treatment protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gene expression After 4-6 months of bone grafting Relative gene expression level | — |
Secondary
| Measure | Time frame |
|---|---|
| Immunohistochemistry After 4-6 months of bone grafting Immunohistochemistry | — |
Countries
Thailand
Contacts
Public ContactAtithan Termworasin
Faculty of Dentistry, Chulalongkorn University
Outcome results
None listed