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Predictability of central venous to arterial CO2 difference (AVCO2) and inflammatory markers in children with cardiac surgery to poor outcomes

Predictability of central venous to arterial CO2 difference (AVCO2) and inflammatory markers in children with cardiac surgery to poor outcomes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20240615004
Enrollment
154
Registered
2024-06-15
Start date
2021-08-16
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

children age 1 days - 18 year old who undergone open cardiac surgery carbon dioxide

Interventions

Any children with either congenital or acquired heart disease who plan to undergone open heart surgery and will return to PICU for post operative care
Diagnostic
Children underwent open heart surgery

Sponsors

Research Fund, faculty of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Days to 18 Years

Inclusion criteria

Inclusion criteria: 1. Children aged 0-18 years old with either congenital or acquired cardiac disease 2. Undergone cardiopulmonary bypass for cardiac surgery 3. Be admitted in PICU for post-operative care

Exclusion criteria

Exclusion criteria: 1. Preterm infant (GA < 37 weeks) or weight less than 2 kg 2. Patient who weaned off cardiopulmoanry bypass and required extracorporeal membrane oxygenator (ECMO) before leaving the operating room 3. Patient who required emergency cardiac operation within 24 hour after hospitalization 4. Patient who had significant residual left side outflow tract obstruction (e.g., coarctation of aorta, interrupted aortic arch) which defined by difference of SBP between upper and lower extremities more than 10 mmHg 5. Patient who had already participated in another research project 6. Patient who does not have both arterial line and central line catheter back from operating room 7. Parents or legal guardian refuse to inform consent.

Design outcomes

Primary

MeasureTime frame
low cardiac output related outcomes 24 hour post operation composite outcomes which include both clinical and laboratory value

Secondary

MeasureTime frame
28-free day mechanical ventilator 28 days post operation the number of days patients were alive and free from ventilatorwithin 28 days by counting the day of first operative night as the first day,28-free ICU day 28 day post operation the number of days patients were alive and free from ICU stay within 28 days by counting the day of first operative night as the first day,28-free inotrope day 28 day post operation the number of days patients were alive and free from inotrope within 28 days by counting the day of first operative night as the first day

Countries

Thailand

Contacts

Public ContactUtcharee Intusoma

Faculty of Medicine, Prince of Songkla University

medpsu.ec@gmail.com074451157

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026