patients with the luminal subtype breast cancer metastasis breast cancer phosphatidylinositol 3-kinase luminal subtype
Conditions
Interventions
PI3K expression was considered overexpressed if staining expression (2+ to 3+) was found in more than 25% of tumor cells in cancer specimens. ,PI3K expression was considered not overexpressed if stain
Basic Science,Basic Science
PI3K expression positive,PI3K expression negative
Sponsors
Self funding
Eligibility
Sex/Gender
Female
Age
17 Years to 65 Years
Inclusion criteria
Inclusion criteria: The Inclusion Criteria included female breast cancer patients aged 17 to 65 years with the luminal subtype, a normal BMI, metastatic or non-metastatic disease, and willingness to participate in the study.
Exclusion criteria
Exclusion criteria: Exclusion criteria included luminal subtype breast cancer patients with positive HER2/Neu immunohistochemistry examinations, the presence of other malignancies (colorectal cancer, liver cancer, lung cancer, brain cancer), or tissue samples not suitable for immunohistochemistry examination (discohesion, denaturation).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PI3K expression After patients underwent surgery immunohistochemistry examination | — |
Secondary
| Measure | Time frame |
|---|---|
| Characteristic data, histopathological grading and metastasis (presence or absence). When patien admitted to our hospital age, sex, histopathological grading (I, II, or III) and metastasis (presence or absence). | — |
Countries
Indonesia
Contacts
Public ContactYusfitaria Alvina
Universitas Hasanuddin
Outcome results
None listed