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Evaluating the Effects of Chlorhexidine and Vitamin C Mouthwash on Oral Health in Non-Surgical Periodontal Therapy: A Randomized Trial

Evaluating the Effects of Chlorhexidine and Vitamin C Mouthwash on Oral Health in Non-Surgical Periodontal Therapy: A Randomized Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240610004
Enrollment
69
Registered
2024-06-10
Start date
2013-12-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis Chlorhexidine Gingival Inflammation Mouthwash Plaque Index Vitamin C

Interventions

Antiseptic fenol agent Listerine Original mouthwash ,Antiseptic bisbiguanide agent CHX-only Signal Professional mouthwash ,Antiseptic bisbiguanide agent CHX+Vit.C Signal Professional mouthwash
Antiseptic fenol agent ,Antiseptic bisbiguanide agent CHX-only,Antiseptic bisbiguanide agent CHX+Vit.C

Sponsors

Ordu University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 35 Years

Inclusion criteria

Inclusion criteria: Presence at least 20 teeth in mouth, No usage of any orthodontic or prosthetic apparatus, Patients who diagnosed as gingivitis, No history of periodontitis, No allergies, Without any systemic diseases that may affect the study outcomes and wound healing.

Exclusion criteria

Exclusion criteria: Smokers, Presence of any uncontrolled systemic disease, History of radiotherapy in head and neck region, Current chemotherapy treatment, Current corticosteroid usage, Presence of metabolic or systemic bone disease, Pregnancy and breast feeding.

Design outcomes

Primary

MeasureTime frame
Plaque index 14 days score

Secondary

MeasureTime frame
Gingival index 14 days score,Modified stain index 14 days score,Bleeding was performed by probing measurements 14 days percentage

Countries

Turkey

Contacts

Public ContactNurdan Ozmeric

Gazi University

nurdan@gazi.edu.tr5332306640

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026