Dry mouth patients Xerostomia, Hyposalivation, Drymouth, HA-pNIPAM, nanogel, Saliva substitute
Conditions
Interventions
New saliva substitute spray product that contain Hy-N solution PF.,Biotene formulation has been reported to have some benefits in reducing xerostomia-related symptoms.,The placebo spray has the same i
Experimental Dietary Supplement,Active Comparator Dietary Supplement,Placebo Comparator Dietary Supplement
Hy-N spray,Biotene spray,Placebo spray
Sponsors
Graduate school Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.The patients aged 18 years or older 2.Patients who reported feeling uncomfortable due to dry mouth 3.Ability to understand and communicate in writing or speaking
Exclusion criteria
Exclusion criteria: 1. Smoker (smoke greater than or equal to 15 cigarettes/day) 2. Alcohol drinker four drinks of alcohol/day 3. Usage of drugs that stimulate saliva flow (pilocarpine and cevimeline) 4. Burning mouth syndrome patients 5. Oral infection condition 6. Refusal to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| saliva flow rate and pH of saliva 7 days after used intervention Weight of unstimulated saliva flow rate for 5 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Xerostomia questionnaire 7 days after used intervention and 3 days washout period questionnaire | — |
Countries
Thailand
Contacts
Public ContactNongnapat Eakpunyakul
Faculty of Dentistry, Chulalongkorn University
Outcome results
None listed