Healthy volunteers who have normal levels of glucose and triglycerides. Glucose response Postprandial plasma glucose Insulin response Postprandial plasma insulin Triglyceride response Postprandial serum triglyceride
Conditions
Interventions
Thai custard (Mo Kaeng) with Bacillus coagulans freeze dried (equivalent to 2,000,000,000 - 5,000,000,000 CFU), inulin 8.5 g, polydextrose 8.5 g, maltitol 35 g, and Lou han guo 45 mg.
The intervention
Active Comparator Other,Placebo Comparator Other
Synbiotic Thai custard (Mo Kaeng) with sugar substitutes,Control Thai custard
Sponsors
Department of Food Chemistry, Faculty of Pharmacy, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Healthy volunteers 2. Age between 18 to 40 years 3. Body mass index (BMI) between 18.5 - 22.9 kg/m2 4. Fasting blood glucose not more than 100 mg/dL 5. Fasting blood triglyceride not more than 150 mg/dL 6. Not had any major illnesses in the past 3 months
Exclusion criteria
Exclusion criteria: 1. Presentation of chronic diseases such as diabetes mellitus, hypercholesterolemia, liver and kidney disease. 2. Immunocompromised conditions 3. Using medications, herbs, or supplements that could affect nutrient absorption, glucose level, lipid, or carbohydrate metabolism. 4. Allergy to an ingredient in the products (including duck egg, pandanus leaves, coconut sugar mixed with cane sugar, maltitol, luo han guo, coconut milk, inulin, polydextrose, soybean oil, taro, and B. coagulans) 5. Smoking 6. Alcohol users 7. Pregnancy 8. Lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma glucose response 0 - 120 minutes after intake the sample Postprandial plasma glucose by enzymatic colorimetric test (glucose oxidase and peroxidase oxidation) | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum insulin response 0 - 120 minutes after intake the sample Postprandial serum insulin level by human insulin ELISA kit ,Serum triglyceride response 0 - 240 minutes after intake the sample Postprandial serum triglyceride level by enzymatic method (glycerol phosphate oxidase) | — |
Countries
Thailand
Contacts
Public ContactSaran Soison
Faculty of Pharmacy, Mahidol University
Outcome results
None listed